PDT-PDAC Project

Photodynamic therapy to meet the challenge of treating pancreatic cancer

Coordinators

CNRS Délégation Centre-Est 

Keywords

Summary

Pancreatic cancer (PDAC) has reached a therapeutic impasse. Survival rates for patients with PDAC have barely improved over the past 50 years, highlighting the urgent need to develop new therapeutic solutions. Photodynamic therapy (PDT) is a promising strategy for the treatment of PDAC. The interdisciplinary PDT-PDAC project aims to gain a better understanding of the impact of the interaction of light and photoactivatable compounds on biological processes to optimize targeted treatment. We propose the design of 3rd generation photosensitizers and excitable nanoplatforms for targeted treatment of PDAC by PDT, which can be induced by excitation with 1 or 2 photons, Cerenkov, X-rays, or ultrasound, independent of the amount of ambient oxygen.

Scientific expectations

Consortium

PDT-PDAC project publications



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